AVINEW

GALLIMUNE

HAEMOVAX

MAREK

 

AVINEW Live vaccine against Newcastle disease VG/VA Strain – Freeze-dried pellet.

 

Composition:The vaccinal strain is the VG/GA strain of Newcastle disease virus. Each dose contains at least 15 PD90 (protecive dose 90%)

 

Doses: Use within 2 hours after reconstitution with antiseptic and/or disinfectant free drinking water.

 

Route of administration and dosage:

 

Individual vaccination:

1> Ocular route: Place a drop of the vaccine solution on the eye of the chicken, wait until the drop spreads properly, then free the chicken.

2> Beak dipping (nasal route) - (only for 1 day old chicken): Dip the beak into the solution up to nostril level so that the solution can penetrate the nasal ducts.

 

Mass vaccination:

1> Drinking water (oral route) - (from the 4th day): Prepare the vaccine solution immediately prior to use by adding the amount of drinking water normally absorbed within one to two hours. All chickens to be vaccinated should be deprived of drinking water for two hours before vaccination.

2> Aerosol– spraying (respiratory route): Spray the vaccine solution above the chicken using a pressure sprayer capable of producing microdroplets.

 

Vaccination schedule

Primary vaccination as from 1 day of age.

Boosters:

Broilers: possible booster 2-3 weeks later Future breeders and layers: boosters 2-3 weeks and 7-8 weeks later; then booster with an inactivated vaccine administered prior to the onset of egg production.

This standard vaccination schedule can be adapted according to the local epidemiological challenge conditions.

 

 GALLIMUNE ND: Inactivated vaccine against Newcastle disease.

 

Composition: The vaccine contains inactivated Newcastle disease virus, a preservative and an oil excipient.

 

Indication: Active immunization of breeding stock against Newcastle disease as a booster for the respective existing vaccines.

 

Administration and dosage:

Shake well prior to use Subcutaneous and/or intramuscular route

Dosage: one 0.3 ml dose per chicken.

One single injection 2 to 4 weeks prior to the laying season.

Packaging: Bottle 300 ml contains 1000 doses.

 

 HAEMOVAX adjuvanted inactivated vaccine for avian haemophilosis (infectious coryza)

 

Composition:

Haemophilus paragallinarum type A, Haemophilus paragallinarum type C: q.s. to obtain a seroconversion index of at least 0.6log10 in chickens.

Al+++ (as hydroxide): 0,63 ± 0,1 mg

Thiomersal, at most: 0.03 mg

0.15M sodium chloride solution, q.s: 0.3 ml

 

Indication: Vaccination of future layer and future breeder pullets against infectious coryza.

 

Administration and dosage:

Shake well prior to use

Subcutaneous and/or intramuscular route

One 0.3 ml dose per chicken Two injections at 3 to 6 weeks interval, the second one being performed at the latest 3 weeks prior to the beginning of the laying period.

 

Packaging:

Box contains 10 bottles, each bottle 1000 doses.

 

 MAREK’S DISEASE VACCINE Serotype 3, Live Virus:

Recommended for subcutaneous vaccination of healthy one-day-old chickens. It is essential that the chickens be maintained under good environmental conditions and that exposure to disease viruses be reduced as much as possible.

 

CRD 92	HEPARENOL	PHOSRETIC	RONAXAN 5%
SUPER LAYER	VETOPHOS	TRISULMIX

 

CRD 92: oral treatment against mycoplasmaosis and their bacterial complications.

 

Composition per 100g:

Oral powder

Spiramycin (as adipic mixture) - 50 million I.U.*

Trimethoprim - 5g

* 15.625g of spiramycin titrating 3200 I.U./mg

(i.e.: Spiramycin: 500 000 I.U./g – Trimethoprim: 50 mg/g)

 

Properties: CRD 92 is the combination of a bacteriostatic antibiotic belonging to the macrolides group, spiramycin and a diaminopyrimidine: trimethoprim, a synthetic antibacterial.

Spiramycin and trimethoprim have both an activity against Gram-positive and Gram-negative organisms. The species usually susceptible to the combination (to be check by in vitro testing) are:

- Gram-positive: Staphylococci, Streptococci...

- Gram-negative: colibacilli, Pasteurella, Salmonella, Bordetella, Haemophilus, Klebsiella, Campylobacter, spirochetes...

- Other orgainsms: mycoplasmas, Toxoplasma, Chlamydiae...

The modes of action of these two active components are different. Spiramycin interferes with protein synthesis by binding to the 50S subunit of the ribosome. Trimethoprim inhibits the dihydrofolate reductase, enzyme indispensable to the synthesis of bacterial nucleoproteins. Follow oral administration, spiramycin and trimethoprim are rapidly absorbed. Diffusion occurs into most body tissues and fluids (except cephalorachidian fluid for spiramycin). Both undergo metabolic inactivation in the liver. Excretion is in the urine for trimethoprim, and in the urine and bile with enterohepatic cycling for spiramycin.

 

Indication: : infection caused by or associated with organisms sensitive to spiramycine and trimethoprim.

 

Administration route and dosage:

Oral, in drinking water or liquid feed.

100 000 I.U. of spiramycin and 10 mg of trimethoprim per kg per day corresponding to 0.2 g of CRD 92 per kg of live weight and per day.

Starting chicks: 0.75 to 1 g of CRD 92 per litre of drinking water.

Adjust dosage to the real water

 

Package:

Box of 100g

Box of 1kg

Bucket of 2.5 kg

 

HEPARENOL: Liver tonic.

 

Composition per 100 ml:

Drinkable solution

Sorbitol : 35 g

Acetyl methionine : 10 g

Choline chloride : 7.5 g

Betain : 6 g

Lysine HCl : 2 g

Flavoured excipient containing plant extracts (artichoke, gentia, boldo)

 

Properties:

Sorbitol: stimulates bilary functions therefore nutriments assimilation (especially emulsification of fats and absorption of fat-soluble vitamins: A, D, K and E).

Acetylmethionine: hydrolysed in vivo, it releases Methionine, a sulphur containing amino acid, which is an essential constituent of the diet, lipotropic and protecting the hepatic cell.

Choline: an acetylcholine precursor, involved in lipid metabolism.

Betain: methyl containing amino acid, its lipotropic function avoid fatty liver.

Lysine: an aliphatic amino acid which is an essential constituent of the diet.

By improving and stimulating hepatic, bilary and intestinal functions, HEPARENOL facilitates the digestion of all nutriments and the elimination of toxins during intensive production period or when changing diets.

 

Doses:

Mix HEPARENOL in feed or drinking water.

1 to 2 ml per 10 kg L.W Horses, cattle: 20 to 50 ml per day.

Sheep, goats, calves: 5 to 15 ml per day.

Swine: 10 to 30 ml per day

Rabbits, poultry: 1 to 2 ml per litre of drinking water

For 5 to 10 consecutive days

 

Packaging:

Bottle of 1 litre, can of 5 litres

 

PHOSRETIC :

 

Composition per 100g::

Oral powder

Ethanol b aminophosphoric acid : 10g

Sodium benzoate : 10g

Excipient containing vitamins A, K3, E, C, lactose.

(i.e.: ETAP: 0.1 g/g – Sodium benzoate: 0.1 g/g)

 

Properties:

Ethanol b aminophosphoric acid (ETAP) (phosphorylcholamine) is a molecule present in low quantities in almost all cells of the body. Being a precursor of main phospholipids, which are part of the cell membranes, it play a very important biological part. It acts directly on the cell regeneration especially in target organs such as the liver and kidney. It is also a source of organic phophorus essential for a rapid tissue regeneration.

After transformation, ETAP will also supply non-organic phosphorus which can be use by the bones, in various organs and in metabolic processes.

Vitamin A, K3, E, C all these vitamins are well known to strengthen the epithelial structures, to combat hemorrhages and therefore to maintain the first line of defense in case of parasitic, infectious or any attack. This allows the animals to better endure stress (heat, transport …).

PHOSRETIC is therefore well adapted to the preventive and curative treatment of all processes inducing lesions in the liver and/or kidney (lithiasis, parasitism, microbial infections, aggressive substance e.g. anticoccidials, sulphonamides …) and of phosphorus deficiencies.

 

Indication: Calves, lambs, kids, foals, swine, poultry, rabbits: product supplying phosphorus.

 

Dosage:

Poultry, rabbits: 1 g per lit of drinking water

Calves, lambs, kids, swine, foals: 1 g per 10 kg of live weight

For 3 to 5 consecutive days

 

Packaging:

of 10 sachets of 100 g, box of 1 kg, bucket of 2.5 kg

 

RONAXAN 5%:

 

Composition per 100g:

Oral powder

Doxycycline (as hyclate) - 5g

i.e. doxycycline (as hyclate) 50mg/g

 

Indication: Infections produced by pathogens sensitive to doxycycline:

- Preventive and curative treatment of respiratory and digestive infections in calves.

- Preventive and curative treatment of respiratory infections in poultry.

- Treatment of respiratory infections in pigs.

 

Administration and dosage:

Oral, in drinking water or liquid feed.

Doxycycline: 10 mg per kg and per day, i.e. 1 g of RONAXAN P.S 5% per 5 kg live weight.

Particular case of poultry:

- Less than 2 weeks old: 1 g per litre of drinking water and per day.

- More than 2 weeks old: 2 g per litre of drinking water and per day.

For:

- Prevention: 1 to 3 days.

- Treatment: 3 to 5 days.

 

Packaging: Box of 100 g, box of 1 kg

 

 SUPER LAYER: All bacterial disease caused by sensitive organisms. SUPER LAYER is specially recommended in case of drops in egg production and to increase performances

 

Composition per 100 g:

Oxytetracyline HCl - 6mg

Vitamin A - 400 000 U.I

Vitamin D3 - 70 000 U.I

Vitamin E - 100mg

Vitamin K3 - 150mg

Vitamin B2 - 250mg

Vitamin B12 - 500mg

Pantothenate canxi - 600mg

Vitamin PP - 1.5g

DL-Methionine - 2.5g

Lysine - 4.5 g

 

Dose:

Preventive treatment: 1 g per litre of drinking water or 1 – 2 kg per tonne of feed.

Curative treatment: 2 to 3 g per litre of drinking water. For 3 to 5 consecutive days.

Adjust dosage to the real water consumption of the birds.

 

Package: 100g / bottle

 

 VETOPHOS : source of trace elements to be supplied at birth, weaning, during growth and intensive production periods.

 

Composition:

Drinkable solution

Garanteed analysis per 100 ml

Phosphorus : 10 g

Calcium : 0.32 g

Magnesium : 2.3 g

Copper : 19 mg

Manganese : 20 mg

Zinc : 360 mg

Iron : 6.5 g

 

Doses:

Piglets: 5 ml per day (diluted with 1 litre of water), for 5 consecutive days, when 3 weeks old.

Fattening pigs: 20 ml per day (diluted with 4 to 5 litres of water), for 5 consecutive days, when 60-70 kg weight.

 

Packaging:

Bottle of 1 little, can of 5 litres

 

TRISULMIX Liquide : Oral sulphadimethoxine – trimethoprim combination

 

Composition per 100 g:

Drinkable solution

Sulphadimethoxine sodium - 20g

(equivalent to 18.6 g of sulphadimethoxine base)

Trimethoprim - 4g

Methyl parahydroxybenzoate - 0.1g

Propyl parahydroxybenzoate - 0.01g

(i.e.: Sulphadimethoxine sodium: 200 mg/ml – Trimethoprim: 40 mg/ml)

 

Properties: LIQUID is the combination of a sulphonamide:

sulphadimethoxine and a diaminopyrimidine: trimethoprim Sulphadimethoxine and trimethoprim act both on the folic acid synthesis of the organism but on different enzymatic steps, inducing an inhibition of the folinic acid formation. Folinic acid is required for the synthesis of DNA. This sequential blockage produces a real bactericidal synergistic activity.

The antimicrobial spectrum of sulphadimethoxine is relatively wide including Gram-positive and Gram-negative organisms and coccidian. The species usually susceptible (to be check by in vitro testing) are:

- Gram-positive organisms: staphylococci, Listeria...

- Gram-negative organisms: E. coli, Klebsiella, Enterobacter, Salmonella, Proteus, Shigella, Haemophilus, Bordetella, Pasteurella, Vibrio cholerae...

- Other organisms: Toxoplasma gondii, coccidia.

Following oral administration, sulphadimethoxine and trimethoprim are rapidly and almost completely absorbed. Both drugs diffuse widely into all tissues, secrections and fluids including cerebrospinal fluid and bronchial secrections. Sulphadimethoxine is highly protein bound (80-85%). The drug is notable for producing sustained serum concentrations with an elimination half-life of about 11 – 15 h (sulphadiazine: 3 h). metabolism of both active components takes place in the liver with acetylation. Excretion is mainly in the urine.

 

Indications: Infections caused by or associated with microorganisms susceptible to the combination sulphadimethoxine - trimethoprim

 

Dosage:

1 to 2 ml per 10 kg of live weight (i.e.: 1 to 2 ml per litre of drinking water).

For 5 consecutive days.

Adjust dosage to the real water consumption of the animals.

 

Package: Bottle of 1 litre, can of 5 litre.